Systematic (IUPAC) name
CAS number 14636-12-5
ATC code H01BA04
PubChem CID 72081
DrugBank EXPT03310
Chemical data
Formula C52H74N16O15S2 
Mol. mass 1227.37 g/mol
Pharmacokinetic data
Protein binding ~30%
Therapeutic considerations
Pregnancy cat.  ?
Legal status  ?
Routes IV

Terlipressin is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It has been found to be effective when norepinephrine does not help.

Indications for use include norepinephrine-resistant septic shock[1] and hepatorenal syndrome.[2] In addition, it is used in bleeding esophageal varices.[3]

Terlipressin is marketed under the brand names Haemopressin (IS Pharmaceuticals), Variquel (IS Pharmaceuticals) or Glypressin (Ferring Pharmaceuticals).


Terlipressin is currently not available in the United States,[4] or Canada.[5]

See also


  1. O'Brien A, Clapp L, Singer M (2002). [Expression error: Missing operand for > "Terlipressin for norepinephrine-resistant septic shock"]. Lancet 359 (9313): 1209–10. doi:10.1016/S0140-6736(02)08225-9. PMID 11955542. 
  2. Uriz J, Ginès P, Cárdenas A, Sort P, Jiménez W, Salmerón J, Bataller R, Mas A, Navasa M, Arroyo V, Rodés J (2000). [Expression error: Missing operand for > "Terlipressin plus albumin infusion: an effective and safe therapy of hepatorenal syndrome"]. J Hepatol 33 (1): 43–8. doi:10.1016/S0168-8278(00)80158-0. PMID 10905585. 
  3. Ioannou G, Doust J, Rockey D (2003). [Expression error: Missing operand for > "Terlipressin for acute esophageal variceal hemorrhage"]. Cochrane Database Syst Rev: CD002147. doi:10.1002/14651858.CD002147. PMID 12535432. 
  4. "{1} And {2} Report Fast Track Designation For Terlipressin In Type 1 Hepatorenal Syndrome - News, Search Jobs, Events". http://www.biospace.com/news_story.aspx?NewsEntityId=19774820. 
  5. "Drug Product Search". 

Template:Pituitary and hypothalamic hormones and analogues

de:Terlipressin pl:Terlipresyna

  • Currently 0.00/5

Rating: 0.0/5 (0 votes cast) login to rate

Add to Favorite Print This Page Publish on Twitter
Bookmark and Share
close about Number of comments per page:
Time format: relative absolute
You need JavaScript enabled for viewing comments