Template:Infobox Disease The B-cell lymphomas are types of lymphoma affecting B cells. Lymphomas are "blood cancers" in the lymph glands. They develop more frequently in older adults and in immunocompromised individuals (such as those with AIDS).
B-cell lymphomas include both Hodgkin's lymphomas and most non-Hodgkins lymphomas. They are often divided into indolent (slow-growing) lymphomas and aggressive lymphomas. Indolent lymphomas respond rapidly to treatment and are kept under control (in remission) with long-term survival of many years, but are not cured. Aggressive lymphomas usually require intensive treatments, but have good prospects for a permanent cure.
Prognosis and treatment depends on the specific type of lymphoma as well as the stage and grade. Treatment includes radiation and chemotherapy. Early-stage indolent B-cell lymphomas can often be treated with radiation alone, with long-term non-reoccurrence. Early-stage aggressive disease is treated with chemotherapy and often radiation, with a 70-90% cure rate. Late-stage indolent lymphomas are sometimes left untreated and monitored until they progress. Late-stage aggressive disease is treated with chemotherapy, with cure rates of over 70%.
There are fourteen kinds of lymphomas involving B cells.
Five account for nearly three out of four patients with non-Hodgkin lymphoma:
- Diffuse large B cell lymphoma
- Follicular lymphoma
- Mucosa-Associated Lymphatic Tissue lymphoma (MALT)
- Small cell lymphocytic lymphoma (overlaps with Chronic lymphocytic leukemia)
- Mantle cell lymphoma (MCL)
The remaining nine are much less common:
- Burkitt lymphoma
- Mediastinal large B cell lymphoma
- Waldenström macroglobulinemia
- Nodal marginal zone B cell lymphoma (NMZL)
- Splenic marginal zone lymphoma (SMZL)
- Extranodal marginal zone B cell lymphoma
- Intravascular large B cell lymphoma
- Primary effusion lymphoma
- Lymphomatoid granulomatosis
Additionally, some researchers separate out lymphomas that appear result from other immune system disorders, such as AIDS-related lymphoma.
- ↑ 1.0 1.1 1.2 Merck Manual home edition, Non-Hodgkin Lymphomas
- ↑ 2.0 2.1 "The Lymphomas" (PDF). The Leukemia & Lymphoma Society. May 2006. p. 12. http://www.leukemia-lymphoma.org/attachments/National/br_1161891669.pdf. Retrieved 2008-04-07.
- ↑ Mazen Sanoufa, Mohammad Sami Walid, Talat Parveen (2010). [Expression error: Missing operand for > "B-Cell Lymphoma of the Thoracic Spine Presenting with Spinal Cord Pressure Syndrome"]. JOCMR 2 (1): 53–54. doi:10.4021/jocmr2010.02.258w.
- ↑ "HMDS: Hodgkin's Lymphoma". http://www.hmds.org.uk/hl.html. Retrieved 2009-02-01.
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