AIDS-related lymphoma

  • Currently 0.00/5

Rating: 0.0/5 (0 votes cast) login to rate

Add to Favorite Print This Page Publish on Twitter
Bookmark and Share
AIDS-related lymphoma
Classification and external resources
MeSH D016483
GeneReviews 2=

AIDS-related lymphoma describes lymphomas occurring in patients with acquired immunodeficiency syndrome (AIDS).[1][2]

A lymphoma is a type of cancer arising from lymphoid cells. In AIDS, the incidences of non-Hodgkin's lymphoma, primary cerebral lymphoma and Hodgkin's disease are all increased.

Contents

Non-Hodgkin's lymphoma

Non-Hodgkin's lymphoma (NHL) is present in about 3% of HIV positive people at the time of their diagnosis of HIV. 20% of HIV positive patients will develop NHL.

Primary cerebral lymphoma

Primary cerebral lymphoma (or primary central nervous system lymphoma) is a form of NHL. It is very rare in immunocompetent people, with an incidence of 5-30 cases per million person-years. However the incidence in immunocompromised individuals is greatly increased, up to 100 per million person-years.

Primary cerebral lymphoma is strongly associated with Epstein-Barr virus (EBV). The presence of EBV DNA in cerebrospinal fluid is highly suggestive of primary cerebral lymphoma.

Treatment of AIDS patients with antiretroviral drugs reduces the incidence of primary cerebral lymphoma.

Hodgkin's disease

The incidence of Hodgkin's disease in the general population is about 10-30 per million person-years. This increases to 170 per million person-years in HIV positive patients.

See also

References

  1. Besson C, Goubar A, Gabarre J, et al. (October 2001). [Expression error: Missing operand for > "Changes in AIDS-related lymphoma since the era of highly active antiretroviral therapy"]. Blood 98 (8): 2339–44. doi:10.1182/blood.V98.8.2339. PMID 11588028. 
  2. Rigolet A, Bossi P, Caumes E, et al. (September 2001). [Expression error: Missing operand for > "Caractéristiques épidémiologiques et évolution de l'incidence des lymphomes cérébraux primitifs observés chez 80 patients infectés par le VIH entre 1983 et 1999 [Epidemiological features and incidence trends of primary cerebral lymphomas observed in 80 HIV-infected patients from 1983 to 1999]"] (in French). Pathologie-biologie 49 (7): 572–5. doi:10.1016/S0369-8114(01)00206-1. PMID 11642021. 

External links


  • Currently 0.00/5

Rating: 0.0/5 (0 votes cast) login to rate

Add to Favorite Print This Page Publish on Twitter
Bookmark and Share
close about Number of comments per page:
Time format: relative absolute
You need JavaScript enabled for viewing comments